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Educational tool only. Does not confirm eligibility or provide medical advice. Always consult your physician before pursuing any trial.

RheumatologyICD-10: M05

Find Recruiting Clinical Trials for Rheumatoid Arthritis

Search biologic, JAK inhibitor, and combination therapy RA trials matched to your treatment history and disease activity.

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About Rheumatoid Arthritis

Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disease primarily affecting the joints, leading to synovitis, cartilage damage, and bone erosion. Treatments include conventional DMARDs (methotrexate, hydroxychloroquine), biologics (anti-TNF, IL-6, abatacept, rituximab), and JAK inhibitors (tofacitinib, baricitinib, upadacitinib).

What Types of Rheumatoid Arthritis Clinical Trials Exist?

RA clinical trials test new biologics, JAK inhibitor combinations, bispecific antibodies, and strategies for drug tapering in remission. Many trials require inadequate response to methotrexate or anti-TNF biologics and specific disease activity scores (DAS28, CDAI).

Find Recruiting Rheumatoid Arthritis Trials Near You

Enter your profile and we'll search ClinicalTrials.gov in real time — matching trials to your age, location, and treatment history. Free, no account required.

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Data from ClinicalTrials.gov · Updated in real time · Educational use only

Frequently Asked Questions

What clinical trials are available for rheumatoid arthritis?
Recruiting RA trials include new biologic targets (GM-CSF, IL-6 combinations), next-generation JAK inhibitors, bispecific antibodies, and tapering/remission studies. Most require prior methotrexate or anti-TNF exposure.
Can I join an RA trial if I have not responded to methotrexate?
Yes — inadequate response to methotrexate (MTX-IR) is one of the most common entry criteria for RA trials testing biologics and JAK inhibitors. Many trials are specifically designed for this population.

Data source: All clinical trial information is sourced from ClinicalTrials.gov, the official U.S. registry maintained by the National Library of Medicine. Tidera Health is an independent educational platform and is not affiliated with ClinicalTrials.gov or the National Library of Medicine. Always verify trial details directly with the research coordinator or your physician.