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Tidera provides educational trial discovery tools and does not provide medical advice or determine eligibility. Always discuss options with your care team.

Clinical Trials for Autoimmune Diseases โ€” Find Recruiting Studies

Search trials for rheumatoid arthritis, lupus, Crohn's disease, ulcerative colitis, MS, psoriasis, and other autoimmune conditions.

๐Ÿ” Search Autoimmune Diseases Trials โ†’

About Autoimmune Diseases Clinical Trials

Autoimmune diseases affect an estimated 23.5 million Americans. Clinical trials in this space test new biologics, JAK inhibitors, small molecules, and cell therapies for conditions ranging from common (RA, IBD, psoriasis) to rare (sarcoidosis, vasculitis, myasthenia gravis). Eligibility typically requires specific disease activity scores, prior treatment failure, and stable background therapy.

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Learning Center: Autoimmune Diseases

Frequently Asked Questions: Autoimmune Diseases Clinical Trials

What is "anti-TNF failure" and how does it affect autoimmune trial eligibility?โ–พ
Anti-TNF failure means you have tried and not adequately responded to a TNF inhibitor biologic (e.g., adalimumab, infliximab, etanercept). Many autoimmune trials specifically require this prior treatment history to test next-line therapies.
Do autoimmune trials require stopping my current biologic?โ–พ
Often yes โ€” most trials require a washout period from prior biologics, typically 4โ€“8 weeks for most agents and longer for monoclonal antibodies with extended half-lives. The trial protocol will specify exact washout requirements.
What disease activity scores are used in autoimmune trials?โ–พ
It varies by condition: DAS28 or CDAI for RA, SLEDAI for lupus, CDAI/SES-CD for Crohn's, Mayo score for UC, PASI/IGA for psoriasis, EASI/IGA for atopic dermatitis, BASDAI for AS. Your rheumatologist tracks these scores.

Data source: All trial data sourced from ClinicalTrials.gov, the official U.S. registry maintained by the National Library of Medicine. Tidera Health is independent and not affiliated with ClinicalTrials.gov or the NLM.