Healthcare Pilot
For Physicians, Coordinators & Healthcare Organizations
Tidera Health is a clinical trial navigation platform for patients. We are exploring structured pilot collaborations with academic medical centers, research coordinators, and patient advocacy organizations.
What Tidera Health Is
Tidera Health is an educational clinical trial discovery and navigation tool. It searches ClinicalTrials.gov in real time, applies structured eligibility pre-filtering, and uses AI to produce plain-English explanations of trial eligibility — presented to patients as match factors, concerns, and suggested questions to ask the research coordinator.
The platform sits at the discovery and navigation layer of the clinical trial recruitment funnel. It does not enroll patients, randomize subjects, process consent, or integrate with clinical workflows. Its purpose is to surface relevant trials patients may otherwise never encounter, and to help them have more informed conversations with their physicians and research teams.
The Clinical Trial Recruitment Problem
of eligible patients enroll in clinical trials
General industry estimate
of clinical trials fail to recruit on time
IQVIA/Tufts CSDD estimates
of patients unaware a relevant trial exists for them
Patient advocacy surveys
The core problem is not trial supply — ClinicalTrials.gov lists thousands of actively recruiting studies at any given time. The problem is a structural information gap: most patients do not know trials exist for their condition, and those who look often cannot parse the dense eligibility language. Tidera Health addresses the awareness and navigation gap, not the clinical workflow.
Current Platform Capabilities
Real-time ClinicalTrials.gov search
Queries the NLM registry live. Results reflect the current recruiting status at time of search — no stale database to maintain.
Structured patient profile intake
Condition, age, sex, location, travel willingness, treatment history, and medication background. All fields optional beyond condition.
Specialty-aware semantic prefiltering
A deterministic rule-based engine screens trials for clear eligibility mismatches (subtype conflicts, biologic-naive requirements, comorbidity-required designs) before AI processing.
AI-assisted plain-English explanations
Claude (Anthropic) reads trial eligibility text and produces fit scores, match factors, potential concerns, medication considerations, and suggested coordinator questions — all with conditional language.
Progressive result delivery
Trial cards appear in ~1–2s. AI enrichment hydrates in stages over 5–15s rather than requiring a full wait. Trials remain useful before AI content arrives.
Direct ClinicalTrials.gov linking
Every result links directly to the authoritative ClinicalTrials.gov study page. Tidera facilitates discovery, not enrollment.
Saved trials (session-local)
Users can bookmark trials within their browser session. No account or server-side storage required.
Print-ready match report
A printable summary of trial matches can be generated for physician office visits.
Specialty Coverage
Semantic prefiltering and AI explanations are calibrated for these specialties. Any condition searchable on ClinicalTrials.gov is supported — specialties below have the highest matching precision.
Oncology
Subtype matching (TNBC, HR+, HER2+), metastatic vs. early-stage, PD-L1/BRCA/MSI biomarker flags
Dermatology
Plaque psoriasis vs. PsA discrimination, biologic-naive/experienced matching, PASI severity
Gastroenterology
IBD (Crohn's / UC), anti-TNF failure alignment, induction vs. maintenance trial context
Neurology
Parkinson's stage detection, observational vs. interventional flagging, Alzheimer's MCI specificity
Rheumatology
Biologic/JAK inhibitor history, MTX-IR alignment, washout detection
Psychiatry
MDD vs. bipolar discrimination, CKD comorbidity contamination filtering, TRD-specific matching
Endocrinology
Type 2 diabetes, HbA1c framing, GLP-1/SGLT2 context
Immunology
Autoimmune overlap handling, biologics history, standard-of-care context
Privacy & Safety Posture
🔒 No protected health information stored
Patient-supplied fields (condition, age, sex, medications, treatment history) are never written to any database, log, or cache. They exist only in the user's browser session for the duration of their search.
🔒 Aggregated analytics only
The only data persisted is: condition searched, location, and result count. No medication names, no age, no sex, no treatment status. Stored in Vercel KV (Upstash Redis) with a 12-hour TTL on explain cache entries.
🔒 AI explanation caching uses privacy-safe keys
Explain cache keys are derived from: condition slug + travel range + treatment tier + medication class flags (boolean only). Medication names are never part of any cache key.
🔒 No user accounts, no tracking pixels, no advertising
Tidera does not use third-party analytics, ad networks, tracking cookies, or persistent user identifiers of any kind.
🔒 ClinicalTrials.gov data only
All trial data originates from ClinicalTrials.gov (NLM/NIH). Tidera does not create, modify, or host trial records. Enrollment happens directly between the patient, their physician, and the research team.
Beta Limitations
We document these clearly because transparency is foundational to healthcare partnerships.
- ⚠AI explanations are estimates, not eligibility determinations. They depend on the quality of eligibility text in ClinicalTrials.gov entries.
- ⚠Trial matching is profile-based. It does not incorporate real-time site capacity, PI availability, or enrollment status beyond the "RECRUITING" filter.
- ⚠The platform does not support direct trial enrollment, patient randomization, or any clinical workflow integration.
- ⚠Long COVID / PASC conditions have limited trial availability in ClinicalTrials.gov regardless of search platform.
- ⚠No EHR integration exists. Patient data is entered manually by the user.
- ⚠The platform is in beta. Accuracy, coverage, and UI will continue to improve based on user feedback.
Interested in a Pilot Collaboration?
We are exploring structured partnerships with academic medical centers, research coordinators, and patient advocacy organizations to validate Tidera Health in real-world recruitment workflows.
Pilot engagements could include: feedback on trial matching accuracy, integration into patient navigation workflows, or advisory input on eligibility interpretation and safety language.
No commitment required. We respond to all pilot inquiries within 48 hours.