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Educational tool only. Does not confirm eligibility or provide medical advice. Always consult your physician before pursuing any trial.

GastroenterologyICD-10: K50

Find Recruiting Clinical Trials for Crohn's Disease

Search IBD studies across biologics, small molecules, and induction/maintenance trials — matched to your treatment history.

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About Crohn's Disease

Crohn's disease is a chronic inflammatory bowel disease (IBD) that can affect any part of the gastrointestinal tract. It is characterized by periods of remission and flare, with symptoms including abdominal pain, diarrhea, fatigue, and weight loss. Treatment options include aminosalicylates, corticosteroids, immunomodulators, biologics (anti-TNF, anti-integrin, IL-12/23 inhibitors), and JAK inhibitors.

What Types of Crohn's Disease Clinical Trials Exist?

Clinical trials for Crohn's disease test new induction and maintenance therapies, combination regimens, and biosimilar options. Many trials require prior anti-TNF failure or biologic exposure, specific disease activity scores (CDAI, SES-CD), and endoscopic confirmation of disease.

Find Recruiting Crohn's Disease Trials Near You

Enter your profile and we'll search ClinicalTrials.gov in real time — matching trials to your age, location, and treatment history. Free, no account required.

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Data from ClinicalTrials.gov · Updated in real time · Educational use only

Frequently Asked Questions

What clinical trials are available for Crohn's disease?▾
Recruiting Crohn's disease trials include studies of biologics (vedolizumab, ustekinumab, risankizumab), JAK inhibitors, small molecules, and combination therapies. Many specifically seek patients who have not responded to anti-TNF therapies like infliximab or adalimumab.
Can I join a Crohn's trial if I failed infliximab?▾
Yes — many Crohn's trials specifically recruit patients who have experienced inadequate response, loss of response, or intolerance to anti-TNF biologics like infliximab. These are sometimes called 'anti-TNF failure' or 'biologic-experienced' criteria.
What disease activity scores are used in Crohn's trials?▾
Common Crohn's disease activity measures used in trial eligibility include the Crohn's Disease Activity Index (CDAI), Simple Endoscopic Score for Crohn's Disease (SES-CD), and stool frequency/abdominal pain sub-scores.

Related Conditions

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Data source: All clinical trial information is sourced from ClinicalTrials.gov, the official U.S. registry maintained by the National Library of Medicine. Tidera Health is an independent educational platform and is not affiliated with ClinicalTrials.gov or the National Library of Medicine. Always verify trial details directly with the research coordinator or your physician.