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Educational tool only. Does not confirm eligibility or provide medical advice. Always consult your physician before pursuing any trial.

RheumatologyICD-10: M32

Find Recruiting Clinical Trials for Lupus (SLE)

Search systemic lupus erythematosus, lupus nephritis, and new biologic trials matched to your disease activity.

🔍 Search Lupus (SLE) Trials →

About Lupus (SLE)

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that can affect multiple organ systems, including the skin, joints, kidneys, heart, lungs, and central nervous system. Lupus predominantly affects women of reproductive age. Standard treatments include hydroxychloroquine, corticosteroids, and immunosuppressants (mycophenolate, azathioprine), with belimumab and anifrolumab as approved biologics.

What Types of Lupus (SLE) Clinical Trials Exist?

Lupus clinical trials test new biologics (B-cell targeted, interferon pathway inhibitors, complement inhibitors), combination regimens, and CAR-T cell therapies. Lupus nephritis trials specifically focus on renal involvement. SLEDAI or BILAG disease activity scores commonly determine trial eligibility.

Find Recruiting Lupus (SLE) Trials Near You

Enter your profile and we'll search ClinicalTrials.gov in real time — matching trials to your age, location, and treatment history. Free, no account required.

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Data from ClinicalTrials.gov · Updated in real time · Educational use only

Frequently Asked Questions

What clinical trials are available for lupus?▾
Recruiting lupus trials include new biologics (anifrolumab combinations, B-cell depletion, complement inhibitors), CAR-T cell therapies, and lupus nephritis-specific studies. Many trials require minimum disease activity scores (SLEDAI ≥6).
Are there lupus trials specifically for kidney involvement?▾
Yes. Lupus nephritis is a common severe manifestation of SLE and has dedicated clinical trials testing new induction and maintenance therapies. These typically require biopsy-confirmed nephritis.
Does hydroxychloroquine affect lupus trial eligibility?▾
Most lupus trials allow continued hydroxychloroquine use (it is considered standard background therapy). However, some trials require a stable dose for several weeks before enrollment. Check with the research coordinator.

Related Conditions

Rheumatoid ArthritisSjögren SyndromeCrohn's Disease

Data source: All clinical trial information is sourced from ClinicalTrials.gov, the official U.S. registry maintained by the National Library of Medicine. Tidera Health is an independent educational platform and is not affiliated with ClinicalTrials.gov or the National Library of Medicine. Always verify trial details directly with the research coordinator or your physician.