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Educational tool only. Does not confirm eligibility or provide medical advice. Always consult your physician before pursuing any trial.

PsychiatryICD-10: F41

Find Recruiting Clinical Trials for Anxiety

Search generalized anxiety, social anxiety, and panic disorder trials — matched to your treatment history.

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About Anxiety Disorders

Anxiety disorders are the most prevalent mental health conditions worldwide, affecting approximately 284 million people globally. They encompass generalized anxiety disorder (GAD), social anxiety disorder (SAD), panic disorder, and specific phobias. First-line treatments include SSRIs, SNRIs, and cognitive behavioral therapy (CBT), but 30–40% of patients do not achieve adequate response with standard treatments, driving substantial clinical trial activity for novel pharmacological and psychological interventions.

What Types of Anxiety Disorders Clinical Trials Exist?

Clinical trials for anxiety test new pharmacological agents including novel anxiolytics, glutamate modulators, GABA-B agonists, and partial serotonin agonists. Non-pharmacological trials include digital CBT platforms, transdiagnostic therapies, mindfulness-based interventions, and neuromodulation. Most trials require a primary anxiety disorder diagnosis confirmed by structured interview (MINI or SCID), minimum severity on GAD-7 or HAMILTON Anxiety Scale, and documentation of prior treatment attempts.

Find Recruiting Anxiety Disorders Trials Near You

Enter your profile and we'll search ClinicalTrials.gov in real time — matching trials to your age, location, and treatment history. Free, no account required.

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Data from ClinicalTrials.gov · Updated in real time · Educational use only

Frequently Asked Questions

What clinical trials are available for anxiety disorders?▾
Recruiting anxiety trials include studies of novel anxiolytics, next-generation SSRIs and SNRIs, glutamate-targeting agents, GABA modulators, digital CBT platforms, mindfulness-based programs, and neuromodulation approaches such as TMS. Many trials target treatment-resistant anxiety — patients who have not adequately responded to two or more standard treatments.
Does my specific anxiety diagnosis affect trial eligibility?▾
Yes. Trials typically target a specific anxiety disorder — GAD, social anxiety disorder, or panic disorder — rather than anxiety broadly. A confirmed diagnosis by a mental health professional using standardized criteria is usually required. Some trials use transdiagnostic approaches that accept multiple anxiety presentations.
Can I join an anxiety trial if I am already on medication?▾
It depends on the trial. Some anxiety trials allow continuation of stable antidepressant therapy and test an add-on treatment. Others require a washout period off psychotropic medications before enrollment. Check eligibility criteria carefully, and always consult your prescriber before stopping any medication.

Related Conditions

Depression (MDD)PTSDBipolar Disorder

Data source: All clinical trial information is sourced from ClinicalTrials.gov, the official U.S. registry maintained by the National Library of Medicine. Tidera Health is an independent educational platform and is not affiliated with ClinicalTrials.gov or the National Library of Medicine. Always verify trial details directly with the research coordinator or your physician.