🧬Tidera Health
⚕️

Educational tool only. Does not confirm eligibility or provide medical advice. Always consult your physician before pursuing any trial.

PulmonologyICD-10: J45

Find Recruiting Clinical Trials for Asthma

Search severe asthma, eosinophilic asthma, and biologic trials — matched to your phenotype and treatment history.

🔍 Search Asthma Trials →

About Asthma

Asthma is a chronic inflammatory airway disease affecting over 262 million people worldwide and 25 million Americans. It is characterized by variable airflow obstruction, bronchospasm, and airway hyperresponsiveness. While mild-to-moderate asthma is well-controlled with inhaled corticosteroids and bronchodilators, severe asthma — affecting 5–10% of patients — remains poorly controlled despite optimized standard therapy and drives the majority of clinical trial activity. Biologic therapies targeting type 2 inflammation (anti-IgE, anti-IL-5, anti-IL-4/13, anti-TSLP) have transformed severe eosinophilic and allergic asthma management.

What Types of Asthma Clinical Trials Exist?

Asthma clinical trials are highly active in severe and biologic-refractory disease. New biologics targeting TSLP (tezepelumab), IL-33, IL-25, and novel oral small molecules are in development. Fixed-dose combination inhaler studies, oral corticosteroid-sparing trials, bronchial thermoplasty studies, and digital symptom monitoring trials are also recruiting. Blood eosinophil count, FeNO (fractional exhaled nitric oxide), IgE level, and prior biologic history determine eligibility for most severe asthma trials.

Find Recruiting Asthma Trials Near You

Enter your profile and we'll search ClinicalTrials.gov in real time — matching trials to your age, location, and treatment history. Free, no account required.

Search Asthma Trials →

Data from ClinicalTrials.gov · Updated in real time · Educational use only

Frequently Asked Questions

What clinical trials are available for asthma?▾
Recruiting asthma trials include novel biologics (anti-IL-33, anti-IL-25, next-generation anti-TSLP), oral small molecules, fixed-dose inhaler combination studies, oral corticosteroid-sparing trials, bronchial thermoplasty studies, and digital health monitoring programs. Severe and uncontrolled asthma patients have the most trial options.
What is eosinophilic asthma and how does it affect trial eligibility?▾
Eosinophilic asthma is characterized by elevated blood eosinophils (typically ≥150–300 cells/µL) and/or elevated FeNO (≥25 ppb), indicating type 2 airway inflammation. Most biologic asthma trials require eosinophil or FeNO thresholds. Non-eosinophilic or type 2-low asthma has fewer targeted biologic options but is an active area of unmet need research.
What spirometry values do I need for asthma trial eligibility?▾
Most asthma trials require pre-bronchodilator FEV1 ≥40–50% predicted (confirming preserved lung function), plus post-bronchodilator reversibility ≥12% and 200 mL (confirming variable obstruction). Severe obstruction or fixed airflow limitation may affect eligibility. Bring your most recent pulmonary function test (PFT) results.

Related Conditions

COPDAtopic DermatitisChronic Sinusitis

Data source: All clinical trial information is sourced from ClinicalTrials.gov, the official U.S. registry maintained by the National Library of Medicine. Tidera Health is an independent educational platform and is not affiliated with ClinicalTrials.gov or the National Library of Medicine. Always verify trial details directly with the research coordinator or your physician.